Genetic basis of calcifying cystic odontogenic tumors
نویسندگان
چکیده
منابع مشابه
Genetic basis of calcifying cystic odontogenic tumors
Calcifying cystic odontogenic tumors (CCOTs) are benign cystic tumors that form abnormally keratinized ghost cells. Mutations in CTNNB1, which encodes beta-catenin, have been implicated in the development of these tumors, but a causal relationship has not been definitively established. Thus, mutational hot spots in 50 cancer genes were examined by targeted next-generation sequencing in 11 sampl...
متن کاملRecurrent Peripheral Calcifying Cystic Odontogenic Tumor (Calcifying Odontogenic Cyst)
Peripheral calcifying cystic odontogenic tumor (PCCOT) is a rare odontogenic lesion, which represents about 1% of jaw cysts. Here we report clinicopathologic, radiographic and CT scan images of a new case of recurrent large PCCOT located in mandibular gingiva in a 77-year-old male with history of a nodular mass in the same area, which had been completely excised 3 years ago. In reviewing the...
متن کاملRecurrent Peripheral Calcifying Cystic Odontogenic Tumor (Calcifying Odontogenic Cyst)
Peripheral calcifying cystic odontogenic tumor (PCCOT) is a rare odontogenic lesion, which represents about 1% of jaw cysts. Here we report clinicopathologic, radiographic and CT scan images of a new case of recurrent large PCCOT located in mandibular gingiva in a 77-year-old male with history of a nodular mass in the same area, which had been completely excised 3 years ago. In reviewing the li...
متن کاملCalcifying Cystic Odontogenic Tumor with Compound Odontoma
Calcifying cystic odontogenic tumor (CCOT) previously known as calcifying odontogenic cyst (COC) is a relatively rare lesion. It was first reported as a separate pathologic entity by Gorlin et al in 1962 as a likely analog of the cutaneous calcifying epithelioma of Malherbe or pilomatricoma. Because of the diverse clinicohistologic features and the various neoplastic potential, there have been ...
متن کاملCalcifying Cystic Odontogenic Tumor: Case Report
The following is a report of a 16-year-old boy with history of pain in the maxillary left central incisor and in the maxillary sinus area. Radiographs showed a w e l l d e m a r c a t e d , u n i l o c u l a r m i x e d radiolucent-radiodense lesion.
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2017
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0180224